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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKC All Species: 10
Human Site: S32 Identified Species: 16.92
UniProt: Q9UQB9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQB9 NP_001015878.1 309 35591 S32 Q T A Q Q P S S P A M R R L T
Chimpanzee Pan troglodytes XP_001142357 309 35587 S32 Q T A Q Q P S S P A M R R L T
Rhesus Macaque Macaca mulatta XP_001098364 471 52859 S194 Q T A Q Q P S S P A M R R L K
Dog Lupus familis XP_849906 346 39574 N66 E N S S G I P N F S M R S F T
Cat Felis silvestris
Mouse Mus musculus O88445 282 32888 R29 L G R G K F G R V Y L A R L K
Rat Rattus norvegicus O55099 343 39216 S69 G A T A L Q G S Q S R Q P F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521399 303 34973 D30 K K R Q W S L D D F D I G R P
Chicken Gallus gallus XP_425725 409 46456 E136 S T K K K K E E T K K R Q W S
Frog Xenopus laevis Q6GPL3 368 41997 E89 S H N T A L A E A P K R K F T
Zebra Danio Brachydanio rerio Q6NW76 320 36928 K42 G P G R V P V K S N S K V L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKN7 329 38282 N31 E H Q E P I K N M C L K M M S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01427 305 34731 N28 K G G K F T I N D F E I G R P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q683C9 282 32738 G28 I G K P L G R G K F G H V Y L
Baker's Yeast Sacchar. cerevisiae P38991 367 42927 L93 M I H E N K K L P K F K S L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 63.4 70.5 N.A. 72.4 67.3 N.A. 64.7 52.3 58.1 65.3 N.A. 43.1 N.A. 54.6 N.A.
Protein Similarity: 100 100 64.7 78.9 N.A. 82.5 79.3 N.A. 78.3 62.3 71.1 78.7 N.A. 62.6 N.A. 68.9 N.A.
P-Site Identity: 100 100 93.3 20 N.A. 13.3 13.3 N.A. 6.6 13.3 13.3 13.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 93.3 46.6 N.A. 26.6 26.6 N.A. 13.3 40 26.6 33.3 N.A. 46.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 56.3 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 70.8 55.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 8 8 0 8 0 8 22 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 15 0 8 0 0 0 0 % D
% Glu: 15 0 0 15 0 0 8 15 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 8 22 8 0 0 22 0 % F
% Gly: 15 22 15 8 8 8 15 8 0 0 8 0 15 0 0 % G
% His: 0 15 8 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 8 0 0 0 15 8 0 0 0 0 15 0 0 0 % I
% Lys: 15 8 15 15 15 15 15 8 8 15 15 22 8 0 15 % K
% Leu: 8 0 0 0 15 8 8 8 0 0 15 0 0 43 8 % L
% Met: 8 0 0 0 0 0 0 0 8 0 29 0 8 8 0 % M
% Asn: 0 8 8 0 8 0 0 22 0 8 0 0 0 0 0 % N
% Pro: 0 8 0 8 8 29 8 0 29 8 0 0 8 0 15 % P
% Gln: 22 0 8 29 22 8 0 0 8 0 0 8 8 0 0 % Q
% Arg: 0 0 15 8 0 0 8 8 0 0 8 43 29 15 0 % R
% Ser: 15 0 8 8 0 8 22 29 8 15 8 0 15 0 29 % S
% Thr: 0 29 8 8 0 8 0 0 8 0 0 0 0 0 36 % T
% Val: 0 0 0 0 8 0 8 0 8 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _